Keywords
How to Cite
Abstract
This thesis examines the prevalence and clinical characteristics of anxiety and depressive disorders observed in patients with malignant tumors of the reproductive system during chemotherapy. Psychological stress associated with an oncological diagnosis, the duration of treatment, adverse effects of chemotherapy, and uncertainty regarding disease prognosis may significantly affect patients’ mental health. The study focuses on identifying symptoms of anxiety and depression, assessing their severity, and analyzing their relationship with clinical factors. The findings may have practical significance for the early detection of mental disorders, determining the need for psychological and psychiatric support, and improving the effectiveness of comprehensive treatment in patients with malignant tumors of the reproductive system.
References
1. Zigmond A.S., Snaith R.P. The Hospital Anxiety and Depression Scale. Acta Psychiatrica Scandinavica. 1983;67(6):361–370.
2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-5-TR. Washington, DC: American Psychiatric Association Publishing, 2022.
3. Holland J.C., Breitbart W.S., Jacobsen P.B., Loscalzo M.J., McCorkle R., Butow P.N. Psycho-Oncology. 3rd ed. Oxford University Press, 2015.
4. Aaronson N.K., Ahmedzai S., Bergman B. et al. The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute. 1993;85(5):365–376.
5. Mitchell A.J., Chan M., Bhatti H. et al. Prevalence of depression, anxiety and adjustment disorder in oncological, haematological and palliative-care settings: a meta-analysis. The Lancet Oncology. 2011;12(2):160–174.
6. World Health Organization. Cancer: Key Facts. Geneva: WHO.
7. National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Distress Management. NCCN.