Keywords
How to Cite
Abstract
This article analyzes the biochemical properties of vitamin D, its metabolic processes in the human body, and its strategic role in calcium-phosphorus metabolism. The step-by-step activation of vitamin D in the liver and kidneys, as well as its importance in bone tissue, the immune system, and endocrine homeostasis, are scientifically explained.
In addition, the clinical consequences of vitamin D deficiency, including rickets, osteomalacia, osteoporosis, and decreased immune system function, are discussed. The article also provides information on the role of vitamin D in prevention and treatment in modern medicine, as well as the risks associated with hypervitaminosis.
References
Bender, D. A. (2020). Introduction to Nutrition and Metabolism (6th ed.). CRC Press.
Bikle, D. D. (2014). Vitamin D metabolism, mechanism of action, and clinical applications. Chemistry & Biology, 21(3), 319-329. https://doi.org/10.1016/j.chembiol.2013.12.016
Guyton, A. C., & Hall, J. E. (2020). Textbook of Medical Physiology (14th ed.). Elsevier.
Holick, M. F. (2007). Vitamin D deficiency. New England Journal of Medicine, 357(3), 266-281. https://doi.org/10.1056/NEJMra070553
Nelson, D. L., & Cox, M. M. (2021). Lehninger Principles of Biochemistry (8th ed.). W. H. Freeman.
Rodwell, V. W., Bender, D. A., Botham, K. M., Kennelly, P. J., & Weil, P. A. (2018). Harper’s Illustrated Biochemistry (31st ed.). McGraw-Hill Education.
Ross, A. C., Caballero, B., Cousins, R. J., Tucker, K. L., & Ziegler, T. R. (2014). Modern Nutrition in Health and Disease (11th ed.). Lippincott Williams & Wilkins.
Wacker, M., & Holick, M. F. (2013). Vitamin D - effects on skeletal and extraskeletal health and the need for supplementation. Nutrients, 5(1), 111-148. https://doi.org/10.3390/nu5010111